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Gadoxetic acid

NMR下載 COA and HPLC MSDS下載
names：
Gadoxetic acid
CAS號：
135326-11-3
MDL Number：
MF(分子式)： C23H30GdN3O11 MW(分子量)： 681.75
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

貨品編碼	規格	純度	價格 (￥)	現價(￥)	特價(￥)	庫存描述	數量	總計 (￥)
DBK501851-500mg	500mg		￥ 0.00	￥ 0.00		Get quote	- +	￥ 0.00
DBK501851-100mg	100mg		￥ 0.00	￥ 0.00		Get quote	- +	￥ 0.00

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中文別名	Gadoxetic acid
英文別名	Gadoxetic acid
CAS號	135326-11-3
Inchi
InchiKey
分子式 Formula	C23H30GdN3O11
分子量 Molecular Weight	681.75
溶解度Solubility
性狀	Solid
儲藏條件 Storage conditions

Gadoxetic acid使用注意事項：
1.實驗前需戴好防護眼鏡，穿戴防護服和口罩，佩戴手套，避免與皮膚接觸。
2.實驗過程中如遇到有毒或者刺激性物質及有害物質產生，必要時實驗操作需要手套箱內完成以免對實驗人員造成傷害。
3.取樣品的移液槍頭需及時更換，必要時為避免交叉污染盡可能選擇濾芯吸頭。
4.稱量藥品時選用稱量紙，并無風處取藥和稱量以免揚撒，試劑的容器使用前務必確保干凈，并消毒。
5.取藥品時盡量采用多個藥勺分別使用，使用后清洗干凈。
6.實驗后產生的廢棄物需分類存儲，并交于專業生物廢氣物處理公司處理，以免造成環境污染。
大規格定制：定制產品請將信息發送至sales@bio-fount.com。
Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

產品說明	Atosiban is a synthetic peptide oxytocin antagonist5,1. It resembles oxytocin with has modifications at the 1, 2, 4, and 8 positions. The N-terminus of the cysteine residue is deaminated to form 3-mercaptopropanic acid at position 1, at position 2 L-tyrosine is modified to D-tyrosine with an ethoxy group replacing the phenol , threonine replaces glutamine at postion 4, and ornithine replaces leucine at position 8.It binds to membrane bound oxytocin receptors on the myometrium and prevents oxytocin-stimulated increases in inositol triphosphate production1. This ultimately prevents release of stored calcium from the sarcoplasmic reticulum and subsequent opening of voltage gated calcium channels. This shutdown of cytosolic calcium increase prevents contractions of the uterine muscle, reducing the frequency of contractions and inducing uterine quiescence.Atosiban has more recently been found to act as a biased ligand at oxytocin receptors3,4. It acts as an antagonist of Gq coupling, explaining the inhibition of the inositol triphosphate pathway thought to be responsible for the effect on uterine contraction, but acts as an agonist of Gi coupling. This agonism produces a pro-inflammatory effect in the human amnion, activating pro-inflammatory signal tranducer NF-κB4. It is thought that this reduces atosiban's effectiveness compared to agents which do not produce inflammation as inflammatory mediators are known to play a role in the induction of labour.TargetActionsOrganismAOxytocin receptorantagonistHumansUVasopressin V1a receptorantagonistHumansUVasopressin V1b receptorantagonistHumansUVasopressin V2 receptorantagonistHumans
Introduction	Not Available
Application1
Application2	Antagonist
Application3