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洛美他西

NMR下載 COA and HPLC MSDS下載
names：
Lormetazepam
CAS號(hào)：
848-75-9
MDL Number：
MF(分子式)： C16H12Cl2N2O2 MW(分子量)： 335.185
EINECS: Reaxys Number:
Pubchem ID:13314 Brand:BIOFOUNT

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中文別名	洛美他西
英文別名	Lormetazepam
CAS號(hào)	848-75-9
Inchi	InChI=1S/C16H12Cl2N2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3
InchiKey	CN1C2=C(C=C(C=C2)Cl)C(=NC(C1=O)O)C3=CC=CC=C3Cl
分子式 Formula	C16H12Cl2N2O2
分子量 Molecular Weight	335.185
溶解度Solubility
性狀	Solid
儲(chǔ)藏條件 Storage conditions

Lormetazepam is a DEA Schedule IV controlled substance. Substances in the DEA Schedule IV have a low potential for abuse relative to substances in Schedule III.

產(chǎn)品說(shuō)明	Organoheterocyclic compounds
Introduction	Lormetazepam is a 1,4-benzodiazepinone compound having a methyl substituent at the 1-position, a hydroxy substituent at the 3-position, a 2-chlorophenyl group at the 5-position and a chloro substituent at the 7-position. It has a role as a sedative. It is a 1,4-benzodiazepinone and an organochlorine compound.
Application1	Lormetazepam is a benzodiazepine which reduces central nervous system (CNS) activity2,1. It produces anxiolytic, muscle relaxant, sedative and hypnotic effects. Because it is a short-acting benzodiapine, it does not produce significant sedation after waking.
Application2	Lormetazepam, as a benzodiazepine, binds to the regulatory site between the α and γ subunits of γ-aminobutryic acid (GABA) A receptors with γ2 and α1, α2, α3, or α5 subunits1. This facilitates the opening of the chloride channel allowing chloride ions to flow into the neuron resulting in hyperpolarization. Hyperpolarized neurons require greater simulation to reach their action potential threshold. The general inhibitory effect on neuronal depolarization produces the effects of lormetazepam.TargetActionsOrganismAGABA(A) Receptorpositive allosteric modulatorHumansAGABA(A) Receptor Benzodiazepine Binding SiteligandHumans
Application3	Ligand

洛美他西使用注意事項(xiàng)：
1.實(shí)驗(yàn)前需戴好防護(hù)眼鏡，穿戴防護(hù)服和口罩，佩戴手套，避免與皮膚接觸。
2.實(shí)驗(yàn)過(guò)程中如遇到有毒或者刺激性物質(zhì)及有害物質(zhì)產(chǎn)生，必要時(shí)實(shí)驗(yàn)操作需要手套箱內(nèi)完成以免對(duì)實(shí)驗(yàn)人員造成傷害。
3.取樣品的移液槍頭需及時(shí)更換，必要時(shí)為避免交叉污染盡可能選擇濾芯吸頭。
4.稱(chēng)量藥品時(shí)選用稱(chēng)量紙，并無(wú)風(fēng)處取藥和稱(chēng)量以免揚(yáng)撒，試劑的容器使用前務(wù)必確保干凈，并消毒。
5.取藥品時(shí)盡量采用多個(gè)藥勺分別使用，使用后清洗干凈。
6.實(shí)驗(yàn)后產(chǎn)生的廢棄物需分類(lèi)存儲(chǔ)，并交于專(zhuān)業(yè)生物廢氣物處理公司處理，以免造成環(huán)境污染。
大規(guī)格定制：定制產(chǎn)品請(qǐng)將信息發(fā)送至sales@bio-fount.com。
Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.

警示圖
危險(xiǎn)性
危險(xiǎn)性警示	warning
安全聲明	H319+H336+H360+H361+H362
安全防護(hù)
備注	實(shí)驗(yàn)過(guò)程中防止吸入、食如，做好安全防護(hù)