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Dehydroemetine

NMR下載 COA and HPLC MSDS下載
names：
2-((6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-3-ethyl-9,10-dimethoxy-1,6,7,11b-tetrahydro-4H-pyrido[2,1-a]isoquinoline
CAS號：
4914-30-1
MDL Number：
MF(分子式)： C29H38N2O4 MW(分子量)： 478.63
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Dehydroemetine
英文別名	Dehydroemetine; BT 436; BT-436; BT436; Mebadin; Ro 1-9334; Ro-1-9334; Ro1-9334;
CAS號	4914-30-1
Inchi	InChI=1S/C29H38N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,24-25,30H,6-12,17H2,1-5H3
InchiKey	XXLZPUYGHQWHRN-UHFFFAOYSA-N
分子式 Formula	C29H38N2O4
分子量 Molecular Weight	478.63
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產(chǎn)品說明	Dehydroemetine(CAS:4914-30-1):僅限應(yīng)用于工業(yè)或者科學(xué)研究過程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。
Introduction	Dehydroemetine is a synthetically produced antiprotozoal agent similar to emetine in its anti-amoebic properties and structure.
Application1
Application2
Application3

警示圖
危險(xiǎn)性	Warning
危險(xiǎn)性警示
安全聲明
安全防護(hù)
備注

[1]POWELL SJ, MACLEOD IN, WILMOT AJ, ELSDON-DEW R. THE TREATMENT OF ACUTE AMOEBIC DYSENTERY: TRIALS OF DEHYDROEMETINE, OF DEHYDROEMETINE-BISMUTH-IODIDE, AND OF DEHYDROEMETINE AND DEHYDROEMETINE-BISMUTH-IODIDE IN COMBINATION. Ann Trop Med Parasitol. 1965 Jun;59:205-7. PubMed PMID: 14345285.

[2]Salako LA. The actions of dehydroemetine on isolated guinea-pig atria. Influence of ouabain and calcium. Br J Pharmacol. 1972 Dec;46(4):725-35. PubMed PMID: 4655270; PubMed Central PMCID: PMC1666376.

[3] Jain NK, Madan A, Sharma TN, Sharma DK, Mandhana RG. Hepatopulmonary amoebiasis. Efficacy of various treatment regimens containing dehydroemetine and/or metronidazole. J Assoc Physicians India. 1990 Apr;38(4):269-71. PubMed PMID: 2202709.

[4] Durotoye AO, Salako LA. The effect of dehydroemetine on isolated guinea-pig atria. Br J Pharmacol. 1972 Apr;44(4):723-31. PubMed PMID: 5041451; PubMed Central PMCID: PMC1665990.

[5] Miller HH, Johnson RK, Donahue JD, Jondorf WR. Hepatic drug-metabolizing enzyme activity in rats pretreated with (-)-emetine or (plus or minus)-2,3-dehydroemetine. Biochem J. 1970 Apr;117(3):491-8. PubMed PMID: 4392930; PubMed Central PMCID: PMC1178951.

6: SARDESAI HV, SULE CR, GAVANKAR SS. Clinical trials with dehydroemetine (Ro 1-9334) in acute amebiasis. Indian J Med Sci. 1963 Apr;17:334-45. PubMed PMID: 13991475.7: NANAVATI MB, DAMANY SJ, JOSHI HD. CLINICAL TRIAL OF DEHYDROEMETINE (RO 1-9334) IN AMOEDIASIS. Indian Pract. 1965 Mar;18:259-63. PubMed PMID: 14292163.8: POWELL SJ, WILMOT AJ, MACLEOD IN, ELSDON-DEW R. DEHYDROEMETINE IN THE TREATMENT OF AMOEBIC LIVER ABSCESS. Ann Trop Med Parasitol. 1965 Jun;59:208-9. PubMed PMID: 14345286.9: KAPADIA RM. CARDIOVASCULAR TOXICITY OF DEHYDROEMETINE IN AMOEBIASIS. J Indian Med Assoc. 1964 Nov 16;4

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