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Prenylamine lactate

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names：
Phenethylamine, N-(3,3-diphenylpropyl)-alpha-methyl-, lactate
CAS號：
69-43-2
MDL Number：
MF(分子式)： C27H33NO3 MW(分子量)： 419.57
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Phenethylamine, N-(3,3-diphenylpropyl)-alpha-methyl-, lactate
英文別名	Agozol; Angormin; Prenylamine lactate;
CAS號	69-43-2
Inchi	InChI=1S/C24H27N.C3H6O3/c1-20(19-21-11-5-2-6-12-21)25-18-17-24(22-13-7-3-8-14-22)23-15-9-4-10-16-23;1-2(4)3(5)6/h2-16,20,24-25H,17-19H2,1H3;2,4H,1H3,(H,5,6)
InchiKey	QPOFIDVRLWJICD-UHFFFAOYSA-N
分子式 Formula	C27H33NO3
分子量 Molecular Weight	419.57
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Prenylamine lactate(CAS:69-43-2):僅限應用于工業或者科學研究過程中非醫療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Prenylamine lactate, a drug formerly used in the treatment of angina pectoris but superseded by less hazardous drugs. Prenylamine depletes myocardial catecholamine stores and has some calcium channel blocking activity.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
安全聲明
安全防護
備注

[1]Elizarov SM, Gavrilina AV, Danilenko VN. [Modulation of serine/threonine protein kinase activity in chloramphenicol-resistant mutants of Streptomyces avermitilis]. Mol Biol (Mosk). 2004 May-Jun;38(3):394-403. Russian. PubMed PMID: 15285607.

[2]Pivovarov AS, Drozdova EI, Kotlyar BI. Calmodulin blockers decrease short-term plasticity of the cholinoreceptors of neurons of the edible snail. Neurosci Behav Physiol. 1991 Jul-Aug;21(4):289-95. PubMed PMID: 1721681.

[3] Pivovarov AS, Drozdova EI, Kotliar BI. [Calmodulin blockaders weaken the short-term plasticity of the neuronal cholinoreceptors in the edible snail]. Zh Vyssh Nerv Deiat Im I P Pavlova. 1990 May-Jun;40(3):535-42. Russian. PubMed PMID: 2169160.

[4] Fan JF, Matsuda R, Ishibashi M, Takeda Y. Determination of prenylamine lactate tablets by high performance liquid chromatography. Eisei Shikenjo Hokoku. 1988;(106):91-4. PubMed PMID: 3250662.

[5] Issa AS, Mahrous MS, Salam MA, Soliman N. The use of 2,3-dichloro-5,6-dicyano-p-benzoquinone for the spectrophotometric determination of some cardiovascular drugs. Talanta. 1987 Jul;34(7):670-2. PubMed PMID: 18964385.

6: Onaya T, Takazawa K, Shibata K. The inhibitory effects of calmodulin antagonists on TSH-stimulated thyroid hormone release by mouse thyroid lobes. Endocrinol Jpn. 1987 Feb;34(1):89-95. PubMed PMID: 3038506.7: Leary WP, Asmal AC, Williams P. Prenylamine lactate in the treatment of angina pectoris. Curr Ther Res Clin Exp. 1976 Feb;19(2):180-4. PubMed PMID: 813955.8: Arora R. Prenylamine lactate in angina pectoris. Indian Heart J. 1973 Jan;25(1):62-6. PubMed PMID: 4197199.9: Starey F. [The formation of collaterals in the coronary vascular system of the dog. Experimental proof of the collateral formation in the dog heart following prenylamine-lactate treatment]. Arzneimittelforschung. 1972 Aug;22(8):1317-20. German. PubMed PMID: 4678393.10: Rosenbaum M, Lennon P, Horvath T. The haemodynamic effects of prenylamine lactate. Med J Aust. 1971 May 15;1(20):1053-6. PubMed PMID: 5556989.1

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