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Rp-cAMPS TEA salt
- names：
(2R,6R,7S)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-mercaptotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, triethylammonium salt
- CAS號(hào)：
71774-13-5
MDL Number： - MF(分子式)： C16H28N6O5PS MW(分子量)： 447.47
- EINECS: Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
| 貨品編碼 | 規(guī)格 | 純度 | 價(jià)格 (￥) | 現(xiàn)價(jià)(￥) | 特價(jià)(￥) | 庫存描述 | 數(shù)量 | 總計(jì) (￥) |
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| 中文別名 | (2R,6R,7S)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-mercaptotetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, triethylammonium salt |
| 英文別名 | Rp-cAMPS TEA salt; Rp cAMPS TEA salt; Rp-cAMPS TEA; Rp cAMPS TEA; |
| CAS號(hào) | 71774-13-5 |
| Inchi | InChI=1S/C10H12N5O5PS.C6H15N/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(19-10)1-18-21(17,22)20-7;1-4-7(5-2)6-3/h2-4,6-7,10,16H,1H2,(H,17,22)(H2,11,12,13);4-6H2,1-3H3/p+1/t4?,6-,7?,10+,21+;/m0./s1 |
| InchiKey | OXIPZMKSNMRTIV-FCRSUSRCSA-O |
| 分子式 Formula | C16H28N6O5PS |
| 分子量 Molecular Weight | 447.47 |
| 溶解度Solubility | |
| 性狀 | Solid powder |
| 儲(chǔ)藏條件 Storage conditions | Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). |
| 產(chǎn)品說明 | Rp-cAMPS TEA salt(CAS:71774-13-5):僅限應(yīng)用于工業(yè)或者科學(xué)研究過程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。 |
| Introduction | Rp-cAMPS TEA salt is an activator of cAMP-dependent protein kinase (PKA). |
| Application1 | |
| Application2 | |
| Application3 |
| [1]Kang KB, van der Zypp A, Majewski H. Endogenous nitric oxide attenuates beta-adrenoceptor-mediated relaxation in rat aorta. Clin Exp Pharmacol Physiol. 2007 Jan-Feb;34(1-2):95-10[1]PubMed PMID: 17201742. |
| [2]Hess G. Synaptic plasticity of local connections in rat motor cortex. Acta Neurobiol Exp (Wars). 2004;64(2):271-6. Review. PubMed PMID: 15366258. |
| [3] Grzegorzewska M, Przybylo M, Litynska A, Hess G. Chemically-induced long-term potentiation in rat motor cortex involves activation of extracellular signal-regulated kinase cascade. Brain Res. 2004 Sep 24;1021(2):192-9. PubMed PMID: 15342267. |
| [4] Hayashi M, Kunii C, Takahata T, Ishikawa T. ATP-dependent regulation of SK4/IK1-like currents in rat submandibular acinar cells: possible role of cAMP-dependent protein kinase. Am J Physiol Cell Physiol. 2004 Mar;286(3):C635-46. Epub 2003 Nov 5. PubMed PMID: 14602578. |
| [5] Huang Y, Chan FL, Lau CW, Tsang SY, Chen ZY, He GW, Yao X. Roles of cyclic AMP and Ca2+-activated K+ channels in endothelium-independent relaxation by urocortin in the rat coronary artery. Cardiovasc Res. 2003 Mar;57(3):824-33. PubMed PMID: 12618244. |
6: Haug T, Storm JF. Protein kinase A mediates the modulation of the slow Ca(2+)-dependent K(+) current, I(sAHP), by the neuropeptides CRF, VIP, and CGRP in hippocampal pyramidal neurons. J Neurophysiol. 2000 Apr;83(4):2071-9. PubMed PMID: 10758117.7: Lee AK, Tse A. Mechanism underlying corticotropin-releasing hormone (CRH) triggered cytosolic Ca2+ rise in identified rat corticotrophs. J Physiol. 1997 Oct 15;504 ( Pt 2):367-78. PubMed PMID: 9365911; PubMed Central PMCID: PMC1159917.8: Maggi CA, Giuliani S. Characterization of the apamin- and L-nitroarginine-resistant NANC inhibitory transmission to the circular muscle of guinea-pig colon. J Auton Pharmacol. 1996 Jun;16(3):131-45. PubMed PMID: 8884460.9: Haynes J Jr, Robinson J, Saunders L, Taylor AE, Strada SJ. Role of cAMP-dependent protein kinase in cAMP-mediated vasodilation. Am J Physiol. 1992 Feb;262(2 Pt 2):H511-6. PubMed PMID: 1311530.
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