購(gòu)物車 
-
Saikogenin A
- names：
(3S,4R,4aR,6aR,6bS,8S,8aS,14aR,14bS)-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,14a,14b-octadecahydropicene-3,8-diol
- CAS號(hào)：
5092-09-1
MDL Number： - MF(分子式)： C30H48O4 MW(分子量)： 472.71
- EINECS: Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
| 貨品編碼 | 規(guī)格 | 純度 | 價(jià)格 (￥) | 現(xiàn)價(jià)(￥) | 特價(jià)(￥) | 庫(kù)存描述 | 數(shù)量 | 總計(jì) (￥) |
|---|
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| 中文別名 | (3S,4R,4aR,6aR,6bS,8S,8aS,14aR,14bS)-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,14a,14b-octadecahydropicene-3,8-diol |
| 英文別名 | Saikogenin A; Saikogenin D; |
| CAS號(hào) | 5092-09-1 |
| Inchi | InChI=1S/C30H48O4/c1-25(2)13-14-30(18-32)20(15-25)19-7-8-22-26(3)11-10-23(33)27(4,17-31)21(26)9-12-28(22,5)29(19,6)16-24(30)34/h7-8,21-24,31-34H,9-18H2,1-6H3/t21-,22-,23+,24+,26+,27+,28-,29-,30-/m1/s1 |
| InchiKey | QGNVMEXLLPGQEV-HSFRRAFJSA-N |
| 分子式 Formula | C30H48O4 |
| 分子量 Molecular Weight | 472.71 |
| 溶解度Solubility | |
| 性狀 | Solid powder |
| 儲(chǔ)藏條件 Storage conditions | Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years). |
| 產(chǎn)品說明 | Saikogenin A(CAS:5092-09-1):僅限應(yīng)用于工業(yè)或者科學(xué)研究過程中非醫(yī)療目的，不應(yīng)用于人類或動(dòng)物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。 |
| Introduction | Saikogenin A is an anti-inflammatory drug that is present in the crude extract of a Chinese herbal plant called Tsai-Fu. |
| Application1 | |
| Application2 | |
| Application3 |
| [1]Cheng JT, Tsai CL. Anti-inflammatory effect of saikogenin A. Biochem Pharmacol. 1986 Aug 1;35(15):2483-7. PubMed PMID: 2427082. |
| [2]Zeng B, Liu GD, Zhang BB, Wang SS, Ma R, Zhong BS, He BQ, Liang Y, Wu FH. A new triterpenoid saponin from Clinopodium chinense (Benth.) O. Kuntze. Nat Prod Res. 2016;30(9):1001-8. doi: 10.1080/14786419.2015.1095745. Epub 2015 Oct 29. PubMed PMID: 26511166. |
| [3] Shibata S, Kitagawa I, Fujimoto H. The chemical studies on oriental plant drugs. XV. On the constituents of Bupleurum Spp. (2). The structure of saikogenin A, a sapogenin of Bupleurum falcatum L. Chem Pharm Bull (Tokyo). 1966 Sep;14(9):1023-33. PubMed PMID: 5976509. |
| [4] Shibata S, Kitagawa I, Fujimoto H. The structure of saikogenin A, a sapogenin of Bupleurum species. Tetrahedron Lett. 1965 Oct;(42):3783-8. PubMed PMID: 5842888. |
| [5] Kumazawa Y, Kawakita T, Takimoto H, Nomoto K. Protective effect of saikosaponin A, saikosaponin D and saikogenin D against Pseudomonas aeruginosa infection in mice. Int J Immunopharmacol. 1990;12(5):531-7. PubMed PMID: 2210914. |
6: Nose M, Amagaya S, Ogihara Y. Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane. Chem Pharm Bull (Tokyo). 1989 Dec;37(12):3306-10. PubMed PMID: 2632076.7: Toriniwa Y, Lv X, Kodama Y, Ohizumi Y, Yoshida M, Nakahata N. Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis. J Pharm Pharmacol. 2006 Jun;58(6):859-66. PubMed PMID: 16734988.8: Shibata M, Yoshida R, Motoashi S, Fukushima M. [Pharmacological studies on Bupleurum falcatum L. IV. Some pharmacological effects of crude saikosides, saikogenin A and syrupy residue (author's transl)]. Yakugaku Zasshi. 1973 Dec;93(12):1660-7. Japanese. PubMed PMID: 4798800.9: Shimizu K, Amagaya S, Ogihara Y. Structural transformation of saikosaponins by gastric juice and intestinal flora. J Pharmacobiodyn. 1985 Sep;8(9):718-25. PubMed PMID: 4087133.10: Kodama Y, Xiaochuan L, Tsuchiya C, Ohizumi Y, Yoshida M, Nakahata N. Dual effect of saikogenin D: in vitro inhibition of prostaglandin E2 production and elevation of intracellular free Ca2+ concentration in C6 rat glioma cells. Planta Med. 2003 Aug;69(8):765-7. PubMed PMID: 14531029.1
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