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Y 26611

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names：
Y 26611
CAS號：
143375-60-4
MDL Number：
MF(分子式)： C18H19F2N3O4 MW(分子量)： 379.3638
EINECS: Reaxys Number:
Pubchem ID: Brand:BIOFOUNT

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中文別名	Y 26611
英文別名	Y 26611; Y-26611; Y26611.
CAS號	143375-60-4
Inchi	InChI=1S/C18H19F2N3O4/c19-13-5-11-15(14(20)16(13)22-3-4-27-10(6-21)7-22)23(9-1-2-9)8-12(17(11)24)18(25)26/h5,8-10H,1-4,6-7,21H2,(H,25,26)
InchiKey	MVKGRIHKSLEKTE-UHFFFAOYSA-N
分子式 Formula	C18H19F2N3O4
分子量 Molecular Weight	379.3638
溶解度Solubility
性狀	Solid powder
儲藏條件 Storage conditions	Dry, dark and store at 0-4℃ for short term (days to weeks) or -20℃ for long term (Store correctly 2-3years).

產品說明	Y 26611(CAS:143375-60-4):僅限應用于工業或者科學研究過程中非醫療目的，不應用于人類或動物的臨床診斷以及治過程療，該產品非藥用，非食用。
Introduction	Y 26611 is a biochemical.
Application1
Application2
Application3

警示圖
危險性	Warning
危險性警示
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備注

[1]Sakurai N, Sano M, Hirayama F, Kuroda T, Uemori S, Moriguchi A, Yamamoto K, Ikeda Y, Kawakita T. Synthesis and structure-activity relationships of 7-(2-aminoalkyl)morpholinoquinolones as anti-Helicobacter pylori agents. Bioorg Med Chem Lett. 1998 Aug 18;8(16):2185-90. Erratum in: Bioorg Med Chem Lett 1998 Oct 20;8(20):2937. PubMed PMID: 9873510.

[2]Akter U, Niwa M, Nose T, Kaida T, Matsuno H, Kozawa O, Uematsu T. Effects of several agents on UVB- and UVA plus systemic fluoroquinolone-induced erythema of guinea pig skin evaluated by reflectance colorimetry. Free Radic Biol Med. 1998 May;24(7-8):1113-9. PubMed PMID: 9626565.

[3] Wada K, Saniabadi AR, Umemura K, Nakano M, Ito T, Nakashima M. Direct measurement of superoxide-dependent chemiluminescence from rat skin following UV-dependent fluoroquinolone-induced dermatitis. Free Radic Biol Med. 1995 May;18(5):923-7. PubMed PMID: 7797102.

[4] Kubo S, Matsumoto T, Takahashi K, Haraoka M, Tanaka M, Sakumoto M, Sakamoto Y, Kumazawa J. Enhanced chemiluminescence response of polymorphonuclear leukocytes by new quinolone antimicrobials. Chemotherapy. 1994 Sep-Oct;40(5):333-6. PubMed PMID: 7956457.

[5] Wada K, Saniabadi AR, Umemura K, Takiguchi Y, Nakashima M. UV-dependent quinolone-induced human erythrocyte membrane lipid peroxidation: studies on the phototoxicity of Y-26611, a new quinolone derivative. Pharmacol Toxicol. 1994 Apr-May;74(4-5):240-3. PubMed PMID: 8090693.

6: Araki K, Kuroda T, Uemori S, Moriguchi A, Ikeda Y, Hirayama F, Yokoyama Y, Iwao E, Yakushiji T. Quinolone antimicrobial agents substituted with morpholines at the 7-position. Syntheses and structure-activity relationships. J Med Chem. 1993 May 14;36(10):1356-63. PubMed PMID: 8388467.7: Tomioka H, Sato K, Saito H. [Antimicrobial activity of new quinolones against Mycobacterium avium and Mycobacterium intracellulare determined by the dilution methods using 7H11 agar and Ogawa egg media]. Kekkaku. 1993 May;68(5):367-70. Japanese. PubMed PMID: 8331881.8: Tomioka H, Sato K, Saito H, Ikeda Y. [Antimycobacterial activity of a newly synthesized fluoroquinolone, Y-26611]. Kekkaku. 1992 Jul;67(7):515-20. Japanese. PubMed PMID: 1331603.

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