購物車 
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(2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-2-isopropyl-5-((S)-2-((S)-2-(morpholine-4-sulfonamido)-3-phenylpropanamido)pent-4-enamido)hexanamide
- names：
(2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-2-isopropyl-5-((S)-2-((S)-2-(morpholine-4-sulfonamido)-3-phenylpropanamido)pent-4-enamido)hexanamide
- CAS號：
150351-30-7
MDL Number： - MF(分子式)： C37H61N5O7S MW(分子量)： 719.9745
- EINECS: Reaxys Number:
- Pubchem ID: Brand:BIOFOUNT
| 貨品編碼 | 規(guī)格 | 純度 | 價格 (￥) | 現(xiàn)價(￥) | 特價(￥) | 庫存描述 | 數(shù)量 | 總計 (￥) |
|---|---|---|---|---|---|---|---|---|
| FMK23820-500mg | 500mg | >98% | ￥ 0.00 | ￥ 0.00 | Get quote | ￥ 0.00 | ||
| FMK23820-100mg | 100mg | >98% | ￥ 0.00 | ￥ 0.00 | Get quote | ￥ 0.00 |
| 中文別名 | |
| 英文別名 | PD 134922 |
| CAS號 | 150351-30-7 |
| Inchi | |
| InchiKey | |
| 分子式 Formula | C37H61N5O7S |
| 分子量 Molecular Weight | 719.9745 |
| 溶解度Solubility | |
| 性狀 | |
| 儲藏條件 Storage conditions | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| 產(chǎn)品說明 | (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-2-isopropyl-5-((S)-2-((S)-2-(morpholine-4-sulfonamido)-3-phenylpropanamido)pent-4-enamido)hexanamide(CAS:150351-30-7):僅限應(yīng)用于工業(yè)或者科學研究過程中非醫(yī)療目的，不應(yīng)用于人類或動物的臨床診斷以及治過程療，該產(chǎn)品非藥用，非食用。 |
| Introduction | PD 134922 is a novel HIV-1 protease inhibitors identified by rational selection.The human immunodeficiency virus (HIV-1), associated with the AIDS (acquired immunodeficiency syndrome) epidemic, encodes an aspartyl protease that is essential for polyprotein processing in the virus (Navia et al., 1989). It has been demonstrated that inactivation of the protease either catalytically or by an inhibitor prevents infectious virion formation (Kohl et al., 1988; Darke et al., 1989). The acquired knowledge of key molecular interactions occurring between inhibitors and aspartyl proteases, as well as the structural similarities between HIV-1 protease and human renin was used to rationally select candidates for HIV-1 screening from the pool of analogs designed as renin inhibitors. A minimal number of chosen compounds were tested in an HIV-1 protease assay system. Two structurally novel peptides emerged as potent enzymatic protease inhibitors. |
| Application1 | |
| Application2 | |
| Application3 |
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