-
乙腈【CAS 75-05-8】
NMR COA MSDS - Names:
Acetonitrile
- CAS號:
75-05-8
MDL Number: MFCD00001878 - MF(分子式): C2H3N MW(分子量): 41.05
- EINECS:200-835-2 Reaxys Number:
- Pubchem ID:6342 Brand:BIOFOUNT
| 貨品編碼 | 規格 | 純度 | 價格 (¥) | 現價(¥) | 特價(¥) | 庫存描述 | 數量 | 總計 (¥) |
|---|---|---|---|---|---|---|---|---|
| JY0313-500ml | 500ml | AR | ¥ 58.00 | ¥ 58.00 | Instock | ¥ 0.00 |
| 中文別名 | 乙腈(75-05-8,Acetonitrile);氰甲烷;乙烷腈;色譜乙腈;甲基氰 |
| 英文別名 | Acetonitrile(75-05-8);Methyl cyanide;Cyanomethane;Ethanenitrile |
| CAS號 | 75-05-8 |
| Inchi | InChI=1S/C2H3N/c1-2-3/h1H3 |
| InchiKey | WEVYAHXRMPXWCK-UHFFFAOYSA-N |
| 分子式 Formula | C2H3N |
| 分子量 Molecular Weight | 41.05 |
| 溶解度Solubility | 與水、甲醇、四氯化碳、乙酸甲酯、乙酸乙酯、二氯乙烷及許多非飽和烴類溶劑互溶 |
| 性狀 | 無色透明液體 |
| 儲藏條件 Storage conditions | 密封陰涼處保存。 |
乙腈(75-05-8,Acetonitrile)毒性測試:
| 生物 | 測試類型 | 路線 | 劑量 | 影響 | 參考 |
| women | TDLo | oral | 500 mg/kg (500 mg/kg) | BEHAVIORAL: COMA; CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP; LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Postgraduate Medical Journal., 73(299), 1997 [PMID:9196706] |
| child | TDLo | oral | 800 mg/kg (800 mg/kg) | BEHAVIORAL: HALLUCINATIONS, DISTORTED PERCEPTIONS; BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD; GASTROINTESTINAL: NAUSEA OR VOMITING | American Journal of Emergency Medicine., 9(268), 1991 [PMID:2018601] |
| man | TDLo | oral | 571 mg/kg (571 mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD; GASTROINTESTINAL: NAUSEA OR VOMITING | Acta Pharmacologica et Toxicologica, Supplementun., 41(340), 1977 |
| man | TDLo | oral | 64 mg/kg (64 mg/kg) | BEHAVIORAL: EXCITEMENT | Journal of Toxicology, Clinical Toxicology., 29(447), 1991 [PMID:1749050] |
| human | TCLo | inhalation | 160 ppm/4H (160 mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Toxicology of Drugs and Chemicals, Deichmann, W.B., New York, Academic Press, Inc., 1969, -(65), 1969 |
乙腈(75-05-8,Acetonitrile)實驗注意事項:
1.使用303-98-0實驗前需戴好防護眼鏡,穿戴防護服和口罩,佩戴手套,避免與皮膚接觸。
2.使用303-98-0實驗過程中如遇到有毒或者刺激性物質及有害物質產生,必要時實驗操作需要手套箱內完成以免對實驗人員造成傷害。
3.取樣品303-98-0的移液槍頭需及時更換,必要時為避免交叉污染盡可能選擇濾芯吸頭。
4.稱量藥品時選用稱量紙,并無風處取藥和稱量以免揚撒,試劑的容器使用前務必確保干凈,并消毒。
5.取藥品303-98-0時盡量采用多個藥勺分別使用,使用后清洗干凈。
6.實驗后產生的廢棄物需分類存儲,并交于專業生物廢氣物處理公司處理,以免造成環境污染。
大規格定制:定制產品請將信息發送至sales@bio-fount.com。
Acetonitrile(75-05-8) Experimental considerations:
1. Wear protective glasses, protective clothing and masks, gloves, and avoid contact with the skin during the experiment.
2. The waste generated after the experiment needs to be stored separately, and handed over to a professional biological waste gas treatment company to avoid environmental pollution.
Tag:乙腈(75-05-8,Acetonitrile),乙腈試劑,乙腈中間體,乙腈的作用,乙腈的用途,乙腈的外觀,乙腈的溶解度,乙腈溶劑,乙腈的合成,乙腈的生產,乙腈的MSDS,乙腈的制造,乙腈的注意事項
| 產品說明 | 乙腈(75-05-8)具有極性非質子傳遞溶劑和EC 3.5.1.4(酰胺酶)抑制劑的作用.乙腈可用于制造胰島素,抗生素和維生素,乙腈溶解度,乙腈msds,乙腈結構式詳見主頁. |
| Introduction | Acetonitrile (75-05-8,乙腈) is prepared by heating a mixture of acetamide and glacial acetic acid. It is an important industrial solvent and is mainly used as a medium for organic synthesis. |
| Application1 | 乙腈(75-05-8,Acetonitrile)可用于制造香水。 |
| Application2 | 乙腈(75-05-8,Acetonitrile)用作溶劑,并用于制造其他化學品,纖維,塑料和染色織物。 |
| Application3 | 乙腈(75-05-8,Acetonitrile)可用于制造胰島素,抗生素和維生素等。 |
| 警示圖 | |
| 危險性 | Danger |
| 危險性警示 | |
| 安全聲明 | H225,H302,H312,H319,H332 |
| 安全防護 | P210,P280,P305+P351+P338 |
| 備注 |
| 象形圖 | |
|---|---|
| 信號警告 | Danger |
| GHS危險說明 |
H225: Highly Flammable liquid and vapor [Danger Flammable liquids] H302: Harmful if swallowed [Warning Acute toxicity, oral] H312: Harmful in contact with skin [Warning Acute toxicity, dermal] H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation] H332: Harmful if inhaled [Warning Acute toxicity, inhalation] |
| 防范說明代碼 |
P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P312, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P312, P322, P330, P337+P313, P363, P370+P378, P403+P235, and P501 (The corresponding statement to each P-code can be found at the GHS Classification page.) |
| C13, Compounds with C-O double bounds(C=O)(Chemical Shifts for Oxygen-17,2002) |
| Acetonitrile Adduct Formation as a Sensitive Means for Simple Alcohol Detection by LC-MS(Journal of The American Society for Mass Spectrometry,2014) |
| C8-C100, Nitrogen-oxygen compounds(Chemical Shifts for Oxygen-17,2002) |
| Study of complexation process between N-phenylaza-15-crown-5 with yttrium cation in binary mixed solvents(Journal of Inclusion Phenomena and Macrocyclic Chemistry,2011) |
| Calculation of Vibrational Spectra for Coordinated Thiocyanate Ion in Acetonitrile(Journal of Applied Spectroscopy,2016) |
Adsorption of Acetonitrile on Platinum and its Effects on Oxygen Reduction Reaction in Acidic Aqueous Solutions—Combined Theoretical and Experimental Study
Abstract:Combined theoretical and experimental study of acetonitrile (AcN) adsorption on platinum was performed and its effects on the kinetics of oxygen reduction reaction in HClO4 and H2SO4 solutions were examined. Using periodic density functional theory calculations, it was shown that AcN molecule can interact with Pt surface either through the unsaturated π electron system or via lone electron pair of nitrogen atom. In both cases, adsorption energy decreases upon increasing coverage, while the modification of electronic structure of Pt surface is localized to the adsorption site. By combining the results of the DFT calculations with the results of blank cyclic voltammetry and rotating disk electrode voltammetry in O2-saturated solutions, it was concluded that the effects of AcN on Pt surface chemistry and ORR kinetics are primarily steric in nature. Resulting measured ORR activities of polycrystalline platinum in the presence of AcN are due to the combination of (i) suppression of (bi)sulfate adsorption (in H2SO4 solution), (ii) suppression of surface oxidation (in both H2SO4 an HClO4 solution), and (iii) site blockage by adsorbed AcN (or products of its electrochemical transformations).
Calculation of Vibrational Spectra for Coordinated Thiocyanate Ion in Acetonitrile
Abstract:The impact of the association of lithium cation with NCS– ion in acetonitrile on the vibrational spectrum was studied by the density-functional method in the B3LYP/6-31+G(d,p) approximation. The best agreement between experimental and calculated ionic association data was achieved taking into account the nonspecific solvation, oversolvation, and solubility of ionic complexes within the discrete-continuum model. The microstructures of the thiocyanate ion in a contact ion pair with lithium cation and ion-pair dimer and trimer in acetonitrile were established.
Study of complexation process between N-phenylaza-15-crown-5 with yttrium cation in binary mixed solvents
Abstract:The complexation reaction between Y3+ cation with N-phenylaza-15-crown-5(Ph-N15C5) was studied at different temperatures in acetonitrile–methanol (AN/MeOH), acetonitrile–propanol (AN/PrOH), acetonitrile–1,2 dichloroethane (AN/DCE) and acetonitrile–water (AN/H2O) binary mixtures using the conductometric method. The results show that in all cases, the stoichiometry of the complex is 1:1 (ML). The values of formation constant of the complex which were determined using conductometric data, show that the stability of (Ph-N15C5.Y)3+ complex in pure solvents at 25 °C changes in the following order: PrOH > AN > MeOH and in the case of binary mixed solutions at 25 °C it follows the order: AN–DCE > AN–PrOH > AN–MeOH > AN–H2O. The values of standard thermodynamic quantities (?H °c and ?S °c) for formation of (Ph-N15C5.Y)3+ complex were obtained from temperature dependence of the formation constant using the van’t Hoff plots. The results show that in most cases, the complex is entropy and enthalpy stabilized and these parameters are influenced by the nature and composition of the mixed solvents. In most cases, a non-linear behavior was observed for variation of log Kf of the complex versus the composition of the binary mixed solvents. In all cases, an enthalpy–entropy compensation effect was observed for formation of (Ph-N15C5.Y)3+ complex in the binary mixed solvents.
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